Post by scumbuster on Jul 14, 2018 6:16:22 GMT -5
A study reinforces the viral theory of Alzheimer's
Through experiments with laboratory mice, a team of researchers at Harvard Medical School has found new evidence suggesting that herpesviruses may be behind Alzheimer's .
These viruses are detected early in life and remain inactive somewhere in the body, but as we get older, they almost always migrate to the brain . However, having the virus is not enough to develop the disease because it depends a lot on genetics. Hence, only in some people the infections activate the production of amyloid beta protein , responsible for the formation of plaques that slowly destroy the brain.
According to the coordinator of the experiment, Tanzi, the sowing of amyloid is what causes the formation of plaque and herpesviruses and other microbes can rapidly generate amyloid-β. In addition, he explains that neurons in the brain use this protein to kill or trap viral particles in a "nano-network". In its version of the viral theory, it affects the germ, but in a more determinant way the immune system.
The study is the second in recent weeks to support the idea that viruses play an important role in Alzheimer's disease. The first study also pointed to a higher concentration of herpesviruses in the brains of people who died with Alzheimer's and bet on genetic interaction as the main factor that increases the risk of suffering from the disease.
After the widespread failure of treatments against Alzheimer's that have focused on stopping the production of amyloid-β, this new perspective proposes alternatives such as preventive antimicrobial drugs or vaccines to prevent these microorganisms from reaching the brain.
es-us.vida-estilo.yahoo.com/un-estudio-refuerza-la-teoria-viral-del-alzheimer-135957021.html
Through experiments with laboratory mice, a team of researchers at Harvard Medical School has found new evidence suggesting that herpesviruses may be behind Alzheimer's .
These viruses are detected early in life and remain inactive somewhere in the body, but as we get older, they almost always migrate to the brain . However, having the virus is not enough to develop the disease because it depends a lot on genetics. Hence, only in some people the infections activate the production of amyloid beta protein , responsible for the formation of plaques that slowly destroy the brain.
According to the coordinator of the experiment, Tanzi, the sowing of amyloid is what causes the formation of plaque and herpesviruses and other microbes can rapidly generate amyloid-β. In addition, he explains that neurons in the brain use this protein to kill or trap viral particles in a "nano-network". In its version of the viral theory, it affects the germ, but in a more determinant way the immune system.
The study is the second in recent weeks to support the idea that viruses play an important role in Alzheimer's disease. The first study also pointed to a higher concentration of herpesviruses in the brains of people who died with Alzheimer's and bet on genetic interaction as the main factor that increases the risk of suffering from the disease.
After the widespread failure of treatments against Alzheimer's that have focused on stopping the production of amyloid-β, this new perspective proposes alternatives such as preventive antimicrobial drugs or vaccines to prevent these microorganisms from reaching the brain.
es-us.vida-estilo.yahoo.com/un-estudio-refuerza-la-teoria-viral-del-alzheimer-135957021.html